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AHR antagonist 2

CAS No. 2338747-54-7

AHR antagonist 2( —— )

Catalog No. M32773 CAS No. 2338747-54-7

AHR antagonist 2 is an antagonist of the aryl hydrocarbon receptor. The IC50s for human AHR and mouse AHR are 0.885 and 2.03 nM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    AHR antagonist 2
  • Note
    Research use only, not for human use.
  • Brief Description
    AHR antagonist 2 is an antagonist of the aryl hydrocarbon receptor. The IC50s for human AHR and mouse AHR are 0.885 and 2.03 nM, respectively.
  • Description
    AHR antagonist 2 is a potent aryl hydrocarbon receptor (AHR) antagonist, extracted from patent WO2019101641A1, compound example 1, with IC50s of 0.885 and 2.03 nM for human and mouse AhR.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Aryl Hydrocarbon Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2338747-54-7
  • Formula Weight
    418.37
  • Molecular Formula
    C20H17F3N4O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (597.56 mM; Ultrasonic )
  • SMILES
    C[C@@H](CO)NC(=O)c1cc(nc(n1)-c1cccnc1)-c1ccc(OC(F)(F)F)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Julien LEFRANC, et al. 2-hetarylpyrimidine-4-carboxamides as aryl hydrocarbon receptor anatgonists. WO2019101641A1.
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